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In development for the treatment of autoimmune diseases: deeper B cell depletion is possible. CAR T cell therapy could make the difference

• Overview
• Ongoing BMS trials 

Aiming for more: the need for deeper B cell depletion in autoimmune diseases

• The goal of B cell depletion
• CD19 CAR T cell therapy
• CAR T cells in the body
• Ongoing BMS trials

CAR T cell therapy: could a different approach make a difference in B cell depletion?

• What is CAR T cell therapy?
• CAR T cell therapy for deep B cell depletion
• CAR T cell therapy in various disease states
• Ongoing BMS trials

CAR T cell therapy: a personalized, one-time infusion

• CAR T cell therapy is well-established
• Treatment process
• Collaborative care
• Ongoing BMS trials

Bristol Myers Squibb is deeply committed to unlocking the potential of CAR T cell therapy in autoimmune disease

• Breakfree-1 clinical trial
  • Systemic lupus erythematosus, including lupus nephritis
  • Idiopathic inflammatory myopathies
  • Systemic sclerosis
    

•  Breakfree-2 clinical trial
  • Relapsing forms of multiple sclerosis
  • Progressive forms of multiple sclerosis
  • Myasthenia gravis

• Find a trial and study site